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Command of Evidence SAT question

Reading and Writing · Information and Ideas · Medium · Answer it here, explanation included.

1,5001,0005000Number of beam breaks-410243852668094108122136150Number of Infrared Beam Breaks by Mice Treated with CNO or Saline, by SexMinutes from treatment females with saline males with saline males with CNO females with CNO
  • All values are approximate.
  • The following 4 lines are shown:
    • females with CNO
    • females with saline
    • males with CNO
    • males with saline
  • The females with CNO line: 
    • Begins at negative 4, 500
    • Rises sharply to 10, 735
    • Rises sharply to 24, 1,100
    • Rises sharply to 38, 1,400
    • Falls sharply to 52, 1,000
    • Rises gradually to 66, 1,050
    • Falls gradually to 80, 980
    • Falls sharply to 94, 735
    • Falls gradually to 108, 700
    • Falls sharply to 122, 500
    • Remains level to 136, 500
    • Falls sharply to 150, 350
  • The females with saline line: 
    • Begins at negative 4, 500
    • Rises gradually to 10, 550
    • Falls gradually to 24, 505
    • Falls sharply to 38, 250
    • Falls sharply to 52, 75
    • Rises sharply to 66, 450
    • Falls gradually to 80, 350
    • Falls sharply to 94, 175
    • Remains level to 108, 175
    • Falls gradually to 122, 100
    • Rises gradually to 136, 175
    • Rises gradually to 150, 200
  • The males with CNO line: 
    • Begins at negative 4, 450
    • Rises gradually to 10, 530
    • Rises gradually to 24, 600
    • Falls gradually to 38, 550
    • Falls gradually to 52, 530
    • Falls gradually to 66, 500
    • Falls gradually to 80, 450
    • Remains level to 94, 450
    • Rises gradually to 108, 475
    • Falls sharply to 122, 235
    • Falls gradually to 136, 210
    • Falls gradually to 150, 205
  • The males with saline line: 
    • Begins at negative 4, 400
    • Rises sharply to 10, 505
    • Falls sharply to 24, 350
    • Falls gradually to 38, 275
    • Falls sharply to 52, 100
    • Rises sharply to 66, 225
    • Falls sharply to 80, 75

To investigate the influence of certain estrogen-responsive neurons on energy expenditure, biologist Stephanie Correa et al. treated female and male mice with either saline solution or clozapine-N4-oxide (CNO), which activates the neurons. Monitoring the activity levels of the mice by measuring how frequently the animals broke infrared beams crossing their enclosures, Correa et al. found that the mice in their study showed sex-specific differences in response to neuron activation: blank

Which choice most effectively uses data from the graph to complete the assertion?

ExplanationShow

Choice C is the best answer. The graph shows that the CNO-treated females were way more active than the CNO-treated males, while the saline-treated males and females (the control groups) had very similar activity levels. This supports the claim that there were sex-specific differences in the mice’s response to neuron activation.

Choice A is incorrect. This choice misreads the graph. All four groups of mice started at nearly the same activity level before treatment (see how all four points are very close together at -4 minutes, meaning four minutes before treatment). Choice B is incorrect. This choice doesn’t complete the assertion. The assertion is about the mice’s response to neuron activation, so we need to include the data about the CNO-treated females and males. Choice D is incorrect. This choice misreads the graph. The line for the CNO-treated males does not show a “substantial decline” until around 122 minutes, and there is no “steep increase” afterward.

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